NUU3 GLP365 (36/100, our lowest recent score) rides the Ozempic wave with a “GLP-1 support” capsule. Because it’s marketed for weight and metabolic goals with undisclosed doses, the safety and honesty questions matter more here than on most products. Everything is dated; none of this is medical advice.

The complaint themes

01Undisclosed doses. Berberine, akkermansia and fucoxanthin are marketed on the front, but their amounts aren’t disclosed — you can’t know if you’re getting a studied dose or a trace. The core knock in our review.
02“GLP-1” framing. The name borrows the language of prescription GLP-1 drugs (Ozempic, Wegovy). The ingredients have, at best, preliminary research and are not equivalent to those medications. Treat implied drug-like results skeptically.
03A megadosed B12. The visible label leans on 12,500%-DV B12 plus minerals — label-filler doing marketing work rather than a metabolic mechanism.

Side effects and safety notes

This is the section to read. Berberine, GLP365’s most-studied ingredient, commonly causes digestive side effects — cramping, diarrhea, constipation — and, more importantly, it can interact with medications: it may lower blood sugar (a concern if you take metformin or other diabetes drugs), affect blood pressure, and interfere with drugs processed by the liver’s CYP enzymes (including some statins and cyclosporine). Because GLP365 doesn’t disclose its berberine dose, you can’t gauge that interaction risk. It is not a substitute for a GLP-1 medication, and no supplement should replace a prescribed treatment. If you’re considering it for weight or metabolic reasons — especially if you take any medication, are pregnant or nursing, or have a health condition — talk to your doctor first. That conversation is the honest path, as our alternatives page lays out.

Frequently asked questions

Is NUU3 GLP365 safe?

For many healthy adults its ingredients are used without issue, but there are real caveats: berberine can cause GI side effects and interacts with several medications (diabetes and blood-pressure drugs, some statins, cyclosporine), and GLP365 doesn’t disclose its berberine dose. Talk to your doctor before use, especially if you take any medication.

Is NUU3 GLP365 the same as Ozempic or a GLP-1 drug?

No. It’s a dietary supplement, not a GLP-1 medication, and its ingredients are not equivalent to or a substitute for prescription GLP-1 drugs. The “GLP-1 support” name borrows the language without the evidence.

What are the side effects of NUU3 GLP365?

The most likely come from berberine: digestive upset (cramping, diarrhea, constipation). More important are its drug interactions — it can affect blood sugar and blood pressure and interfere with some medications. Because the dose isn’t disclosed, the interaction risk is hard to gauge.

Sources

  1. NUU3 — GLP365 product page and visible label (berberine/akkermansia/fucoxanthin marketed without disclosed amounts; B12 12,500% DV, iodine, zinc, selenium, vanadium). Checked July 2026. nuu3.com
  2. General medical and pharmacology references on berberine (GI effects; interactions with blood-sugar, blood-pressure and CYP-metabolized medications) and on “natural GLP-1” supplements not being equivalent to GLP-1 drugs. Accessed July 2026; linked live, not republished.
  3. The Ingredient Report — NUU3 GLP365 review (36/100). Checked July 2026.

Update history

Content is for informational purposes only and is not medical advice. Medical disclaimer.