GLP-1 drugs — Ozempic, Wegovy, Mounjaro — are the most talked-about thing in weight loss in a generation. NUU3 GLP365 is one of a wave of supplements borrowing that acronym for the shelf: “GLP-1 Support,” the label promises, above three fashionable ingredient names.
Here is the problem this review is built on. The front of the bottle sells berberine, akkermansia and fucoxanthin — and the product never tells you how much of any of them you’re getting. What the visible label does show is a 12,500%-DV megadose of B12 and a handful of minerals. A drug’s halo, a supplement’s evidence, and undisclosed doses in between. That’s the 36. Read this before you buy.
At a glance
Quick verdict
GLP365’s entire proposition is its three front-label ingredients and the “GLP-1” word above them. So the fact that none of those three ingredients’ amounts are disclosed isn’t a footnote — it’s the review. You are being asked to pay for berberine, akkermansia and fucoxanthin at doses the company won’t print, on the promise that they behave like a prescription drug they are not.
What the label does show doesn’t help its case: a 12,500%-DV B12 dose is a marketing flourish, not a metabolic strategy, and there’s no named third-party testing. 36/100 — the lowest score in this batch — because the product’s core claims are the ones it documents least. If actual GLP-1 effects are your goal, that’s a conversation with a doctor, not a capsule.
A consistent summary of formula, transparency, value and experience. Not a medical rating.
Scores follow our published 100-point methodology, applied identically to every product. View the scoring methodology.
May suit you if
- Honestly, we couldn’t construct the buyer this serves well — the core ingredients’ doses are undisclosed
- If you want berberine specifically, a single-ingredient berberine product with a printed dose is the more honest buy
- If you want gut or metabolic support, real food, fiber and a doctor’s input beat an undisclosed blend
Skip it if
- You want to know how much berberine, akkermansia or fucoxanthin you’re getting — it isn’t disclosed
- You’re treating it as a substitute for or equivalent to a GLP-1 medication — it isn’t one
- You want named third-party testing and honest, stable pricing — neither is here
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Key findings
Product specifications
| Format | Capsules, 2/serving, 60 per bottle (30 servings) |
|---|---|
| Price (checked July 19, 2026) | ~$49.99 (from ~$69.99 list); ~$39.99 subscription |
| Cost per serving | ~$1.33–$1.67 |
| Headline ingredients | Berberine, akkermansia, fucoxanthin — amounts not disclosed |
| Disclosed on label | B12 300 mcg (12,500% DV), iodine 150 mcg, zinc 10 mg, selenium 70 mcg, vanadium 50 mcg |
| Independent testing | None named (non-GMO mark only) |
| Distributed by | NUU3 / MUSU Nutrition, Norwalk, CT |
The formula: a promise without a dose
The ingredients NUU3 leads with aren’t fringe: berberine has real preliminary research on blood sugar, and fucoxanthin (from brown seaweed) and akkermansia (a gut bacterium) are active areas of metabolic study. In principle a well-dosed, well-tested version of this idea could be interesting.
This isn’t that. The amounts of all three headline ingredients are undisclosed — so even if the research were settled, you couldn’t know whether GLP365 contains a studied dose or a trace. What the label does quantify is a supporting cast — a 12,500%-DV B12 dose, iodine, zinc, selenium, vanadium — that reads more like label-filler than a mechanism. Marketing the ingredients you don’t quantify and quantifying the ingredients you don’t market is the inverse of a trustworthy label. Formula 8/25, transparency 7/20.
The testing column
GLP365 shows a non-GMO mark and no independent testing — no NSF, no published certificate of analysis (checked July 19, 2026). For a product making metabolic claims with undisclosed active doses, the absence of any verifiable testing compounds the transparency problem rather than offsetting it. Testing 6/20.
What it’s like to take
We have not run our own trial, and we would caution against treating any experience of this product as evidence it “works like GLP-1” — expectation effects are powerful in weight-loss supplements. One practical note: berberine can cause GI upset (cramping, diarrhea) in some people and can interact with medications, so the undisclosed dose matters for safety, not just efficacy. Experience 5/10.
The math: paying for a name
At about $49.99 a bottle (~$1.67 a serving, ~$1.33 on subscription), discounted from a ~$69.99 list that functions as an anchor, GLP365 is priced like an ordinary supplement. The value problem isn’t the sticker — it’s that you’re paying it for undisclosed doses of the ingredients that supposedly justify the product. Paying a fair price for an unverifiable promise is still poor value. Value 6/15.
Returns and where to buy
Sold on nuu3.com and through Amazon/Walmart listings, with subscription and multi-bottle bundles and aggressive promotional pricing. Direct purchases follow NUU3’s return policy; verify current terms given the discounting model. More important than any policy: GLP-1 “support” supplements are not substitutes for prescription treatment, and berberine can interact with medications — this is a talk-to-your-doctor product (checked July 19, 2026).
What customers report
We read customer feedback across the major platforms and summarize the recurring themes. We don’t republish other platforms’ reviews — check the live sources yourself:
Amazon & DTC reviews
Mixed and promo-driven
Ratings are shaped by heavy promotion and the GLP-1 trend; results claims are anecdotal and unverifiable.
View live reviews →Better Business Bureau
Some billing notes
Complaints that appear cluster on subscription/billing rather than product safety, as of July 19, 2026.
Search the BBB →Independent & medical coverage
Skeptical of GLP-1 supplements
Dietitians and physicians broadly caution that “natural GLP-1” supplements are not equivalent to GLP-1 drugs — the core caution this review scores.
Search expert coverage →We don't fact-check or verify individual customer reviews — reviewers' opinions and experiences are their own, and we never treat them as evidence that a product works or doesn't. We read feedback at scale, report recurring themes, and link the live sources.
Every factual claim on this page that is ours carries a checked date and a source. Spot an error? Tell us — corrections run under our corrections policy.
Reader reports · 0 so far
Share your experienceRight of reply: NUU3 is welcome to respond to this review — including by publishing the doses of berberine, akkermansia and fucoxanthin — on the record. Contact our editorial team — responses are published unedited alongside this review.
What to buy instead
If your goal is the effect GLP-1 drugs produce, the honest path is a conversation with a doctor about whether those medications are appropriate for you — not a capsule that borrows their name. If you want the individual ingredients, a single-ingredient berberine product with a printed dose is a more transparent buy than an undisclosed blend. And for everyday nutrition and gut health, real food and fiber — covered across our produce and greens reviews — do more, more verifiably, than a trend-named capsule. Earth Energy, the brand under common ownership with this site, sells no comparable GLP-1 product, so we recommend none here.
Final assessment
NUU3 GLP365 is the clearest example in this batch of a product whose marketing and whose label point in opposite directions: it sells three trendy ingredients it won’t dose and a drug-borrowed promise it can’t support, while quantifying a B12 megadose that isn’t the point. 36/100 — the lowest here — is what happens when the claims a product leads with are the ones it documents least. If you’re considering it for weight or metabolic reasons, that’s exactly the situation to take to a doctor first: GLP-1 supplements are not GLP-1 medications, and berberine can interact with drugs you may already take.
Frequently asked questions
Is NUU3 GLP365 the same as a GLP-1 drug like Ozempic?
No. GLP365 is a dietary supplement, not a GLP-1 medication. It markets ingredients (berberine, akkermansia, fucoxanthin) with, at best, preliminary metabolic research — and doesn’t disclose their doses. It is not equivalent to or a substitute for prescription GLP-1 drugs.
Does NUU3 GLP365 disclose its ingredient doses?
Not for its headline ingredients. The amounts of berberine, akkermansia and fucoxanthin aren’t disclosed on the product page or visible label. The label does quantify a 12,500%-DV B12 dose plus iodine, zinc, selenium and vanadium.
Is NUU3 GLP365 third-party tested?
No named third-party testing or certification appears — only a non-GMO mark — as of July 19, 2026, which is a notable gap for a product making metabolic claims.
Why did it score 36/100?
Because its central claims are the ones it documents least: undisclosed doses of its headline ingredients, a drug-borrowed “GLP-1” promise the evidence doesn’t support, no named testing, and anchored discount pricing.
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Sources
- NUU3 — GLP365 product page and the bottle we photographed (front-marketed berberine, akkermansia, fucoxanthin with no disclosed amounts; visible label B12 300 mcg / 12,500% DV, iodine 150 mcg, zinc 10 mg, selenium 70 mcg, vanadium 50 mcg; pricing ~$49.99 from ~$69.99 list; NUU3/MUSU Nutrition, Norwalk, CT). Checked July 19, 2026. nuu3.com
- General medical and dietitian coverage of “natural GLP-1” supplements (cautioning they are not equivalent to GLP-1 drugs; berberine GI effects and drug interactions). Accessed July 19, 2026; linked live, not republished.
- The Ingredient Report — produce & greens category comparison and scored reviews, for real-nutrition alternatives. Checked July 19, 2026.
Update history
- July 19, 2026 — Report first published. Visible label and pricing checked this date. We re-score on the record if NUU3 discloses the doses of its headline ingredients or adds named testing.
Content is for informational purposes only and is not medical advice. GLP-1 support supplements are not a substitute for prescription treatment; berberine can interact with medications — talk with your healthcare provider before use. Medical disclaimer.